What is the difference between PRP and PRF?

Both are blood-derived. PRP is centrifuged with anticoagulant and gives liquid plasma with high platelet concentration. PRF (platelet-rich fibrin) is centrifuged without anticoagulant and gives a gel where platelets are caught in a fibrin mesh. PRF releases growth factors more slowly over a longer period.

How many PRP treatments are needed?

Standard is 3 to 4 sessions spaced 4 weeks apart, then maintenance once every 6 to 12 months. The number of sessions depends on indication: hair loss often requires more than facial rejuvenation.

Yes. Because the blood is your own, there is no allergy or rejection risk. Rare side effects are infection from breached sterility and brief redness/swelling on day one. PRP is avoided during pregnancy and in patients with platelet-function disorders.

Does PRP work for hair loss?

Yes. For androgenic alopecia there is good scientific support. The growth factors stimulate the dermal papilla cells of the hair follicle and extend the anagen phase. Effect is best in early-stage hair loss; severe baldness responds less. PRP is often combined with finasteride or minoxidil.

Why is PRP combined with Dermapen?

The microchannels from Dermapen let PRP into the dermis where fibroblasts sit. Topical application without microneedling is blocked by the stratum corneum. The combination is synergistic — better uptake, better results per session.

PRP: glossary | Dibélle

Also known as: platelet-rich plasma, vampire facial

What is PRP?

PRP stands for platelet-rich plasma. The treatment uses the patient's own blood (autologous). About 10 to 30 ml of blood is drawn into a special tube with anticoagulant and centrifuged. This produces three layers: red blood cells at the bottom, a thin buffy coat with platelets and white cells, and plasma on top. The PRP fraction has 4 to 6 times the platelet concentration of normal blood.

How it works in treatment

Platelets contain over 30 different growth factors (PDGF, TGF-β, VEGF, EGF, IGF). When PRP is injected or applied through Dermapen microchannels, the platelets activate and release these factors. The result is stimulated collagen production, increased microcirculation, and faster tissue repair. Because it uses the patient's own cells, allergy risk is essentially zero.

Where it is used

At Dibélle, PRP is used for facial rejuvenation, dark under-eye circles and fine lines, acne scars, and scalp stimulation against hair loss. PRP-face is often combined with Dermapen so the channels can take the product into the dermis. PRP-scalp is injected directly into the sub-galeal tissue where the hair follicles sit. Standard is 3-4 sessions spaced 4 weeks apart.

Results and safety

Results emerge over 4 to 8 weeks and are maintained with one session every 6 to 12 months. Using the patient's own blood eliminates allergy and rejection risk. The most common side effects are bruising, swelling, and redness on the first day. Rare: infection from breached sterility. PRP is not used during pregnancy or in patients with platelet-function disorders.

Common questions about PRP

What is the difference between PRP and PRF?: Both are blood-derived. PRP is centrifuged with anticoagulant and gives liquid plasma with high platelet concentration. PRF (platelet-rich fibrin) is centrifuged without anticoagulant and gives a gel where platelets are caught in a fibrin mesh. PRF releases growth factors more slowly over a longer period.
How many PRP treatments are needed?: Standard is 3 to 4 sessions spaced 4 weeks apart, then maintenance once every 6 to 12 months. The number of sessions depends on indication: hair loss often requires more than facial rejuvenation.
Is PRP safe?: Yes. Because the blood is your own, there is no allergy or rejection risk. Rare side effects are infection from breached sterility and brief redness/swelling on day one. PRP is avoided during pregnancy and in patients with platelet-function disorders.
Does PRP work for hair loss?: Yes. For androgenic alopecia there is good scientific support. The growth factors stimulate the dermal papilla cells of the hair follicle and extend the anagen phase. Effect is best in early-stage hair loss; severe baldness responds less. PRP is often combined with finasteride or minoxidil.
Why is PRP combined with Dermapen?: The microchannels from Dermapen let PRP into the dermis where fibroblasts sit. Topical application without microneedling is blocked by the stratum corneum. The combination is synergistic — better uptake, better results per session.

PRP