Also known as: exosomes, extracellular vesicles
What are exosomes?
Exosomes are extracellular vesicles, small lipid sacs measuring 30 to 150 nanometres. Cells use them to communicate with one another. In aesthetic use the exosomes come from stem cells, most often plant-derived or umbilical-cord. The cargo is growth factors, mRNA, and peptides for repair.
How they work in treatment
When exosomes are taken up by skin fibroblasts and keratinocytes they deliver a signal: build collagen, dampen inflammation, accelerate healing. Exosomes are not stem cells; they are the message stem cells send. That avoids the legal grey zone around stem cell therapy.
Where they are used
At Dibélle, exosomes are applied directly after Dermapen or other microneedling. The microchannels let the product into the dermis. Indications include skin rejuvenation, acne scars, and hyperpigmentation. Topical application without microneedling first gives much weaker results.
Results and safety
Results emerge over 4 to 6 weeks. The safety profile from established suppliers is good, but the field is new and regulation is ongoing. Choose a clinic that can show traceable sourcing and available safety documentation.
Common questions about Exosomes
- Are exosomes the same as stem cells?
- No. Exosomes are the signalling vesicles stem cells release. The treatment delivers the message stem cells send without introducing the cells themselves. That avoids the legal grey zone around stem cell therapy and removes the risk of uncontrolled cell growth.
- Why are exosomes paired with Dermapen?
- The microchannels from Dermapen let exosomes into the dermis where fibroblasts sit. Topical application without microneedling is blocked by the stratum corneum and gives a much weaker result. The combination is synergistic.
- How quickly do results appear?
- A skin glow is often visible within days, but the real effect — thicker dermis, more even tone, fewer fine lines — develops over 4 to 6 weeks once fibroblasts have built new collagen.
- Are exosome treatments safe?
- Safety from established suppliers is good, but the field is new and regulation is still catching up. Choose a clinic that can show traceable sourcing, safety documentation, and GMP certification on the product.