How long does PCL treatment last?

Between 12 and 48 months depending on the product version used. Ellansé S lasts 12 months, M lasts 18, L lasts 24, and E lasts up to 36-48 months. The Polyphil series spans similar ranges.

What is the difference between PCL and PLLA?

Both are synthetic biostimulators. PCL has a longer breakdown time (24-48 months) than PLLA (9-12 months) and a softer structure. PLLA requires multiple sessions; PCL gives initial volume immediately and lasts longer per session.

Can PCL be dissolved?

No, PCL cannot be dissolved enzymatically like hyaluronic acid. The substance breaks down naturally over 24 to 48 months. Correct placement at the time of injection is therefore critical.

Yes. Polycaprolactone has been used in medical implants since the 1970s and is CE-marked for aesthetic use. The most common side effects are swelling and bruising that resolve within days.

Polycaprolactone: glossary | Dibélle

Also known as: PCL, polycaprolactone, Ellansé, Polyphil

What is polycaprolactone?

Polycaprolactone (PCL) is a biocompatible, bioresorbable polymer that has been used in medical implants since the 1970s. In aesthetic use it is supplied as microspheres (25-50 micrometres) suspended in a CMC gel carrier. The best-known brands are Ellansé (4 versions with 12, 18, 24, and 36 months of breakdown time) and the Polyphil series.

How it works in treatment

The gel carrier provides initial volume. The microspheres signal fibroblasts to build type I and III collagen over 6 to 12 months. Once the gel has been absorbed, the collagen carries the volume. PCL differs from PLLA in its longer breakdown time and from CaHA in a softer structure that allows use in more areas.

Where it is used

At Dibélle, PCL is used through the Polyphil line for broad-scale skin tightening on the face, neck, décolletage, hands, and body. The substance suits patients who want longer effect than hyaluronic acid filler without committing to a 25-month treatment like Sculptra.

Results and safety

Results last 12 to 48 months depending on the product version. Initial volume fades over a few weeks as the gel absorbs, then collagen build-up takes over. PCL cannot be dissolved. Correct depth and technique are critical to avoid visible microspheres or nodules. Choose an injector with specific PCL training.

Common questions about Polycaprolactone

How long does PCL treatment last?: Between 12 and 48 months depending on the product version used. Ellansé S lasts 12 months, M lasts 18, L lasts 24, and E lasts up to 36-48 months. The Polyphil series spans similar ranges.
What is the difference between PCL and PLLA?: Both are synthetic biostimulators. PCL has a longer breakdown time (24-48 months) than PLLA (9-12 months) and a softer structure. PLLA requires multiple sessions; PCL gives initial volume immediately and lasts longer per session.
Can PCL be dissolved?: No, PCL cannot be dissolved enzymatically like hyaluronic acid. The substance breaks down naturally over 24 to 48 months. Correct placement at the time of injection is therefore critical.
Is PCL safe?: Yes. Polycaprolactone has been used in medical implants since the 1970s and is CE-marked for aesthetic use. The most common side effects are swelling and bruising that resolve within days.

Polycaprolactone