What is the advantage of PRF over PRP?

PRF releases growth factors slowly over 7 to 14 days versus PRP's release over hours. This gives better regeneration in delicate areas like the eyes and in treatments where sustained stimulation is wanted. PRF also produces less swelling and faster recovery.

Is PRF the same as the vampire facial?

No. The vampire facial usually refers to PRP-face. PRF is a more modern variation of the same principle — using your own blood — but with a fibrin matrix instead of liquid plasma.

Can PRF be used under the eyes?

Yes. The periorbital area is one of PRF's strongest indications. The slow release of growth factors suits thin skin better than PRP's sharp peak. The under-eye treatment for dark circles is often run as a 3-4 session course.

How many PRF treatments are needed?

PRF-cure 4 is the most common protocol — 4 sessions spaced 4 weeks apart. Maintenance every 6 to 12 months depending on indication and result.

How does recovery differ from PRP?

PRF generally produces less swelling and faster recovery because the fibrin matrix holds the plasma in place. Many can return to makeup the next day, compared with 2-3 days after intensive PRP.

PRF: glossary | Dibélle

Also known as: platelet-rich fibrin, i-PRF

What is PRF?

PRF (platelet-rich fibrin) is the second generation of platelet concentrate. The difference from PRP: PRF is centrifuged without anticoagulant. The result is a fibrin mesh that holds platelets, white blood cells, and growth factors. I-PRF (injectable PRF) is the liquid version that can be injected with a thin cannula. Solid PRF is used as a biological scaffold in surgery.

How it works in treatment

The fibrin matrix releases growth factors slowly over 7 to 14 days — compared with PRP where release happens over a few hours. The extended signal gives better tissue regeneration in cases where slow stimulation matters: thin periorbital skin, acne scars, scalp stimulation. PRF also gives less surface swelling and bruising because the fibrin mesh holds the plasma in place.

Where it is used

At Dibélle, PRF is used for the eye area (dark circles, fine lines), acne scars, overall facial skin quality, and scalp stimulation. PRF is often combined with microneedling to allow uptake. PRF-cure 4 is a standard protocol of 4 sessions every 4 weeks.

Results and safety

Results emerge over 6 to 8 weeks. Because the blood is the patient's own, allergy and rejection risk is essentially zero. PRF generally has milder side effects than PRP — less swelling, faster return to daily life. Avoided during pregnancy and in patients with platelet-function or coagulation disorders.

Common questions about PRF

What is the advantage of PRF over PRP?: PRF releases growth factors slowly over 7 to 14 days versus PRP's release over hours. This gives better regeneration in delicate areas like the eyes and in treatments where sustained stimulation is wanted. PRF also produces less swelling and faster recovery.
Is PRF the same as the vampire facial?: No. The vampire facial usually refers to PRP-face. PRF is a more modern variation of the same principle — using your own blood — but with a fibrin matrix instead of liquid plasma.
Can PRF be used under the eyes?: Yes. The periorbital area is one of PRF's strongest indications. The slow release of growth factors suits thin skin better than PRP's sharp peak. The under-eye treatment for dark circles is often run as a 3-4 session course.
How many PRF treatments are needed?: PRF-cure 4 is the most common protocol — 4 sessions spaced 4 weeks apart. Maintenance every 6 to 12 months depending on indication and result.
How does recovery differ from PRP?: PRF generally produces less swelling and faster recovery because the fibrin matrix holds the plasma in place. Many can return to makeup the next day, compared with 2-3 days after intensive PRP.

PRF