Is PRX-T33 the same as a regular TCA peel?

It contains TCA but the mechanism differs. A regular TCA peel produces frosting and flaking. PRX-T33's hydrogen peroxide component prevents surface denaturation so the TCA works in the dermis without visible skin effect on the surface.

Is downtime needed after PRX-T33?

Almost none — light redness on day one. You can apply makeup the next day. This is the product's main advantage over traditional TCA peels which require 5-10 days of flaking.

How many PRX-T33 treatments are needed?

Standard is 4-6 sessions spaced 1-2 weeks apart, then maintenance every 6 months. The short interval is possible because there is no flaking period.

Is PRX-T33 suitable for darker skin tones?

Yes, more suitable than traditional TCA. Because no epidermal inflammation occurs, the PIH risk (post-inflammatory hyperpigmentation) is lower. Fitzpatrick V-VI can be treated with particular caution and pre-treatment.

PRX-T33: glossary | Dibélle

Also known as: PRX T33, WiQo Plus, bioactive peeling

What is PRX-T33?

PRX-T33 is made by Italian WiQo Med and was introduced in 2008 as an entirely new chemical peel concept. The active substance is 33% trichloroacetic acid (TCA) combined with 5% hydrogen peroxide and kojic acid. The hydrogen peroxide 'calibrates' the TCA so it works in the dermis without damaging the epidermis.

How PRX-T33 works

In traditional TCA peeling, the acid denatures protein in the skin's outer layers (frosting), leading to flaking. PRX-T33 prevents surface denaturation through hydrogen peroxide's protective effect — the TCA then works directly in the dermis and triggers collagen and elastin build-up without affecting the skin's outer layer. Kojic acid adds pigment-evening effect.

PRX-T33 at Dibélle

At Dibélle, PRX-T33 features in several protocols: PRX-Dermapen-face (combined with microneedling), PRX-T33 Face (pure peel), PRX-T33 Face/Neck. Suits patients who want effect without downtime. Standard is 4-6 sessions spaced 1-2 weeks apart.

Results and safety

Results emerge over 4-6 weeks and last 3-6 months. Because it is not a traditional peel with flaking, downtime is minimal — light redness on day one. PRX-T33 suits most skin tones including Fitzpatrick V-VI with caution.

Common questions about PRX-T33

Is PRX-T33 the same as a regular TCA peel?: It contains TCA but the mechanism differs. A regular TCA peel produces frosting and flaking. PRX-T33's hydrogen peroxide component prevents surface denaturation so the TCA works in the dermis without visible skin effect on the surface.
Is downtime needed after PRX-T33?: Almost none — light redness on day one. You can apply makeup the next day. This is the product's main advantage over traditional TCA peels which require 5-10 days of flaking.
How many PRX-T33 treatments are needed?: Standard is 4-6 sessions spaced 1-2 weeks apart, then maintenance every 6 months. The short interval is possible because there is no flaking period.
Is PRX-T33 suitable for darker skin tones?: Yes, more suitable than traditional TCA. Because no epidermal inflammation occurs, the PIH risk (post-inflammatory hyperpigmentation) is lower. Fitzpatrick V-VI can be treated with particular caution and pre-treatment.

PRX-T33