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IVO-registered4.9 rating · 1225+ reviews

Profhilo

IBSA's hybrid hyaluronic acid for bio-remodelling. Hydrates deeply and stimulates collagen without adding volume.

Also known as: Profhilo H+L, Profhilo Body, Profhilo Structura, bio-remodelling

What is Profhilo?

Profhilo is an Italian brand from IBSA. The substance is two-fraction hyaluronic acid: 32 mg low molecular weight (L-HA) and 32 mg high molecular weight (H-HA) per syringe. The difference from other HA products: no BDDE or other cross-linking chemical. Stability comes from the NAHYCO process — a heat-treated hybrid complex.

How Profhilo works

Profhilo is described as bio-remodelling and differs from both filler and skin booster. The high HA concentration and hybrid technology give three simultaneous effects: deep hydration (L-HA binds water), structural support (H-HA stabilises the matrix), and biostimulation (gradual collagen and elastin production). Treatment is given at 5 specific BAP points (Bio Aesthetic Points) per side of the face.

Profhilo at Dibélle

At Dibélle, Profhilo is used for patients seeking skin quality rather than volume change — fixed lines, stiffness, general skin papering. Treatment is given as a course of 2 sessions spaced 4 weeks apart, then maintenance every 6 months. Profhilo Structura is a variant for deeper structural support; Profhilo Body for breasts, upper arms, and inner thighs.

Results and safety

Results appear within 2-3 weeks after the second treatment and last around 6 months. Because Profhilo is pure HA without cross-linkers, it has the lowest nodule and migration risk among injectable HA products. The BAP method gives even distribution without point injections. Common side effects: local bumps that resolve over 24-48 hours, mild redness.

Common questions about Profhilo

What is the difference between Profhilo and regular filler?
Profhilo adds no volume — it hydrates and stimulates skin quality. Regular filler is cross-linked HA that fills out tissue. Profhilo suits loose or dry skin; filler suits contour change and volume restoration.
How long does Profhilo last?
Results last around 6 months after a course of 2 sessions. Maintenance is recommended 1-2 times a year. Effect builds over several months and fades gradually.
How many Profhilo treatments are needed?
Standard is 2 sessions spaced 4 weeks apart. Result is judged 2-3 weeks after the second treatment. Maintenance every 6 months is enough for most.
Is Profhilo the same as a skin booster?
Profhilo is a form of skin booster but differs from classic skin boosters through high HA concentration (64 mg/ml total) and the NAHYCO technology that replaces cross-linking chemicals. The effect is stronger and lasts longer than traditional skin boosters.
What are BAP points?
Bio Aesthetic Points — 5 specific injection points per side of the face derived from IBSA's anatomical study. The points sit where HA spreads effectively without risk to vessels or nerves. The standard protocol is 2 ml per side across 5 points.
Can Profhilo be used during pregnancy?
No. As with all injectable treatments, Profhilo is avoided during pregnancy and breastfeeding. There is no safety data for these groups. Wait until after breastfeeding before treatment.